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Research Expertise

Medical Devices and Diagnostics

The following highlights our research expertise in this area:

Antibody-Based Diagnostics for Clinical Chemistry and Bacteriology/Microbiology:
DNA Probes; immunoglobulin gene cloning; immunosensor development.

Biomedical Electronics:
Application of artificial intelligence in diagnostics; medical instrumentation for bioengineering applications; systems for gait analysis; functional electrical stimulation instrumentation; medical signal analysis; medical image analysis software.

Biomedical Signal Processing:
Algorithm development for medical healthcare applications; radiotherapy; MRI; echocardiography; ultrasonic transducer design and development including instrumentation

Cell and Tissue Organ Engineering:
Differentiated immortalised cells for toxicity assessment and therapeutic use- bone cells, liver cells, kidney cells; cellular toxicity assessment; biomaterials; artificial organs; artificial organ design and construction; artificial implant design and evaluation; biomaterials for blood-contacting use; biomedical instrumentation; hybrid artificial organs and devices.

DNA Diagnostics:
Surface enhanced resonance Raman scattering (SERRS)- detection of specific defects in DNA, detection of cystic fibrosis, reliable detection of multiple different DNA sequences in a single sample.

Fluorescence Photophysics:
In-vivo fluorescence lifetime sensing in clinical medicine; research in glucose monitoring.

Forensic Science:
DNA analysis; forensic analysis of weapons and explosives; drug detection.

Genomics and DNA Profiling:
Signal processing for genome analysis Immunodiagnostics: Antibody-based diagnostics for clinical chemistry and bacteriology/microbiology; DNA probes; immunoglobulin gene cloning; immunosensor development.

Inorganic chemistry:
NMR techniques; development of surface enhanced raman spectroscopy (SERRS) for diagnostic applications; NMR of cell/drug interactions; molecular diagnostics; biogenic amines; metal complexes for diagnostic NMR.

Lasers and Optoelectronics:
Laser biophotonics; optically based diagnostic treatment systems; medical instrumentation; ophthalmic diagnostics; multi-photon imaging; laser scanning microscopy.

Medical Diagnostic Devices and Instrumentation:
Point of care diagnostic systems; iontophoretic techniques for non-invasive monitoring and drug delivery; sensors for bioreactors and cell engineering; cellular probe analysis techniques; ophthalmic drug monitoring systems.

Membrane Technology: Membrane bioreactors for artificial liver systems.

Monoclonal Antibodies:
Production and use in diagnostics; catalytic antibodies research.

Orthotics and Prosthetics:
Novel component development; improved treatment methods and devices; clinical auditing of care provision; design and application development; applications of silicone rubber; biomechanics of transfemoral socket design CAD/CAM; casting, cast rectification and alignment repeatability in prosthetics; correction afforded by "sustentaculum tali" rectification; orthotic techniques in cerebral palsy; develop computer software to allow automated data capture of ultrasound image; digital methods to create and store lasts for footwear; evaluation of prosthetic knee units; gait analysis; hydrostatic pressure casting of prosthetic sockets; immersive virtual environments for training powered wheelchair users; influence of prosthetic component choice on rehabilitation of lower limb amputees; introduction and evaluation of pre-preg orthoses; loading of knee-ankle-foot orthoses; lower limb orthotic biomechanics; manufacture of prosthetic components using digital technologies; mechanical support of sprained ankles; mechanical testing of prosthetic sockets; MRI study of soft tissue displacement within two types of socket; neuro-biomechanics pilot study; orthotic management of arthrogryposis multiplex congenita and foot and ankle in stroke; orthotic service outcome measurement; paediatric orthotics; prosthetics outcome measures; psychology and amputation; shape of trans-tibial sockets; survey of packaging posing the greatest opening problems; trials of prototype sensor socket for trans-tibial amputees; ultrasound study of residual femoral movement in transfemoral sockets.

Superconducting Quantum Inference Devices (SQUIDS):
Human physiology studies using SQUID technology (foetal, spinal, neurological and visual system analysis)

Ultrasonics:
Transducer and array design for biomedical applications; ultrasonic drug delivery control systems.

Departments and Specialist Centres

The areas of research described in the above section represent the activities of a number of University departments and specialist centres including:
Pure and Applied Chemistry
Bioscience
Statistics and Modelling Science
Electronics and Electrical Engineering
Institute of Photonics
Immunology
Physics
National Centre for Orthotics and Prosthetics
Bioengineering Unit
Chemical and Process Engineering
Pharmaceutical Sciences
Centre for Ultrasonic Engineering
Strathclyde Institute for Biomedical Sciences
Strathclyde Institute for Drug Research
Cancer Research Campaign Formulation Unit
Centre for Biophotonics